1. An Investigation into the Effects of Diindolylmethane (BioResponse DIM®) Supplementation in Women with Low-Grade Cervical Cytological Abnormalities.
Cancer Research UK
Click Here to Read the Article
Click Here to See Additional Information

2. Diindolylmethane in Healthy Volunteers: Multi Dose Study
University of Kansas

3. Diindolylmethane in Treating Patients With Abnormal Cervical Cells
Barts and the London School of Medicine
London, UK

4. Oral Diindolylmethane (DIM) for the Treatment of Cervical Dysplasia
Sponsor: NYU, New York Downtown Hospital
New York, NY

5. An Open Label Pilot Trial of BioResponse-DIM for the Treatment of Anal Human Papillomavirus Infection
Cornell University,
New York, NY

6. Diindolylmethane in Treating Patients With Nonmetastatic Prostate Cancer That Has Not Responded To Previous Hormone Therapy
Barbara Ann Karmanos Cancer Institute, Wayne State University
Detroit, MI

7. Diindolylmethane in Treating Patients Undergoing Surgery for Stage I or Stage II Prostate Cancer
University of Wisconsin
Madison, WI

Please visit ClinicalTrials.gov for a listing of Clinical Trials using DIM.

• DIM and Prostate Health: Down-regulation of androgen receptor by 3,3'-diindolylmethane contributes to inhibition of cell proliferation and induction of apoptosis in both hormone-sensitive LNCaP and insensitive C4-2B prostate cancer cells.
  
  
• DIM and Breast Health: Gene expression profiling revealed survivin as a target of 3,3'-diindolylmethane-induced cell growth inhibition and apoptosis in breast cancer cells.
  
  
• Benefits of Healthy Estrogen Metabolism: A hormonal association between estrogen metabolism and proliferative thyroid disease.
  
  
• DIM Promotes Immune Function: Activation and potentiation of interferon-gamma signaling by 3,3'-diindolylmethane in MCF-7 breast cancer cells.